Table 4.
Clinical outcomes of T0 and T90 cycles.
| T0 | T90 | Unadjusted p-Value | Adjusted p-Value 1 | |
|---|---|---|---|---|
| Cancelled embryo transfer (%) | 9/77 (12) | 3/77 (4) | 0.068 | 0.614 |
| Absence of fertilized oocytes (%) | 4/77 (5) | 0 | 0.048 | 0.476 |
| Absence of viable embryos (%) | 3/77 (4) | 0 | 0.077 | 0.618 |
| Delayed embryo transfer (freeze-all) (%) | 2/77 (3) | 3/77 (4) | 0.736 | 0.974 |
| N transferred embryos | 1.8 ± 0.6 | 1.5 ± 0.6 | 0.022 | 0.240 |
| Cycles with day 2–3 ET | 65/68 (96%) | 45/74 (61%) | <0.0001 | <0.0001 |
| Implantation (%) | 2/124 (2%) | 15/85 (18%) | <0.0001 | <0.0001 |
| Pregnancy (%) | 2/65 (3%) | 15/45 (33%) | 0.0001 | 0.001 |
| Live-birth rate (%) | 0/124 (0%) | 13/83 (16%) 2 | <0.0001 | <0.0001 |
| Miscarriage (%) | 2/2 (100%) | 0/15 (0%) | <0.0001 | <0.0001 |
| Cycles with day 5 ET | 3/68 (4%) | 29/73 (40%) | <0.0001 | <0.0001 |
| Implantation (%) | 0/4 (0%) | 10/32 (31%) | 0.475 | 0.974 |
| Pregnancy (%) | 0/3 (0%) | 10/29 (34%) | 0.577 | 0.974 |
| Live-birth rate (%) | 0/4 (0%) | 10/32 (31%) | 0.475 | 0.974 |
| Miscarriage (%) | 0% | 0/10 (0%) | - | |
| N ET in freeze–thaw cycles | 3 | 9 | ||
| Implantation (%) | 1/4 (25%) | 4/9 (44%) | 0.974 | 0.974 |
| Pregnancy (%) | 1/3 (3%) | 4/9 (44%) | 0.551 | 0.974 |
| Live-birth (%) | 0/1 (0%) | -/9 3 | - | |
| Miscarriage (%) | 1/1 (100%) | 1/4 (25%) | 0.819 | 0.974 |
| Cumulative pregnancy rate per cycle (%) | 1/71 (2%) | 29/83 (35%) | <0.0001 | |
| Cumulative live-birth rate per cycle (%) | 0/132 (0%) | 23/124 (19%) 4 | <0.0001 | <0.0001 |
| Cumulative miscarriage (%) | 3/3 (100%) | 1/29 (3%) | 0.0001 | 0.001 |
| Cumulative pregnancy rate per couple (%) | 1/77 (1%) | 29/77 (38%) | <0.0001 | <0.0001 |
| Cumulative live-birth rate per couple (%) | 0/77 (0%) | 23/77 (30%) 4 | <0.0001 | <0.0001 |
ET, embryo transfer. 1 Alpha value adjusted by Hochberg stepwise test; 2 n. 2 ongoing clinical pregnancies; 3 n. 3 ongoing clinical pregnancies; 4 n. 5 ongoing clinical pregnancies.