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. 2021 Jul 30;22(15):8180. doi: 10.3390/ijms22158180

Table 2.

Viruses and their effects on mitochondrial dynamics.

S.No. Author & Year Virus Work & Object
1 Horner and Gale, 2013 [98] Hepatitis C virus (HCV) HCV cleaves the MAVS protein and suppresses the host’s antiviral response.
2 Datan et al., 2016 [99], Liang et al., 2016 [100] Dengue and Zika virus With the help of autophagy, the Dengue and Zika viruses improve their replication and the induction of autophagy by pharmacological agents (e.g., rapamycin) increasing viral dissemination.
3 Joubert et al., 2012 [101] Chikungunya virus Autophagy limits virus-induced cell death and in vivo mortality in Chikungunya virus.
4 Datan et al., 2016 [99]; Lee et al., 2008 [102]; McLean et al., 2011 [103] Dengue virus Autophagy inhibits apoptosis to enhance virus replication in the Dengue virus.
5 Zhu et al., 2016 [104] Transmissible gastroenteritis virus (TGEV) TGEV-induced complete mitophagy by stimulating DJ1-1 protein deglycase which increases cell survival and infection by eliminating virus-induced ROS.
6 Meng et al., 2014 [105] Newcastle disease virus (NDV) Delayed administration of 3 methyl adenine (3-MA) induced more efficient oncolysis in NSCLCs.
7 Barbier et al., 2017 [106] Dengue virus In the Dengue virus, mitochondrial fission is blocked because the Dengue virus’ NS4B or NS3 protein promotes mitochondrial fusion by downregulating Drp1.
8 Yu et al., 2015 [107] Dengue virus In the case of the Dengue virus, mitochondrial fusion is suppressed by NS2B3 protease which cleaves MFNs.
9 Zamarin et al., 2005 [108] Influenza A virus PB1-F2 have an essential role in the pathogenicity of the viral infection of influenza virus A, via modulation of the host’s mitochondrial dynamics.
10 Kim et al., 2013b [109] Hepatitis C virus (HCV) HCV stimulates the expression of parkin, PINK1 and induced mitophagy by impairing oxidative phosphorylation. The resulting HCV infection affects mitochondrial dynamics.
11 Gou et al., 2017 [110] Classical swine fever virus (CSFV) CSFV expresses MFN2 and stimulates parkin and PINK1 expression, resulting in enhanced mitochondrial fission and mitophagy.
12 Ding et al., 2017 [111] Human parainfluenza virus type 3 (HPIV3) In HPIV3 infection, a viral protein regulates mitophagy independently of parkin/PINK1.
13 Xia et al., 2014b [112] Measles virus During the measles viral infection, virus-induced antiviral immune response is enhanced by the knockdown of autophagy-related genes (eg, ATG7, BECN1, SQSTM1, and RAB7).