Figure A2.

(Top): Pseudo-colour images of haemoglobin distribution in two normal optic discs (left) and two glaucomas (right) and the normalised environment, which are used for network training. The eyes are always analysed with the temporal region to the left. (Below): The Gradient-weighted Class Activation Maps, known as Grad-CAM saliency map, or heat maps, indicate that the networks seem to be particularly focused on the cup and the upper and lower poles.