Table 1.
Performance of Laguna OnhE, OCT, and perimetry indices.
| GDF | RNFLT | Rim Area | OCT-C/D | MD | PSDr | TCV | |
|---|---|---|---|---|---|---|---|
| AUC | 0.970 | 0.875 | 0.926 | 0.921 | 0.897 | 0.883 | 0.904 |
| SE | 0.0054 | 0.0135 | 0.0104 | 0.0099 | 0.012 | 0.013 | 0.0115 |
| CI | 0.956–0.981 | 0.850–0.897 | 0.906–0.943 | 0.901–0.939 | 0.874–0.917 | 0.859–0.904 | 0.881–0.923 |
| GDF | RNFLT | Rim Area | OCT-C/D | MD | PSD-sLVr | ||
| RNFLT | p < 0.0001 | ||||||
| Rim Area | p < 0.0001 | p < 0.0001 | |||||
| OCT-C/D | p < 0.0001 | p = 0.0006 | p = 0.5812 | ||||
| MD | p < 0.0001 | p = 0.1389 | p = 0.0422 | p = 0.0869 | |||
| PSDr | p < 0.0001 | p = 0.6013 | p = 0.0039 | p = 0.0083 | p = 0.0692 | ||
| TCV | p < 0.0001 | p < 0.0001 | p = 0.0824 | p = 0.1731 | p = 0.5053 | p = 0.0066 |
GDF = Laguna OnhE globin distribution factor; RNFLT = OCT retina nerve fiver layer thickness; OCT-C/D = OCT vertical cup/disc ratio; MD = perimetric mean defect or deviation; PSDr = perimetric pattern standard deviation or square root of loss variance rectified; TCV = perimetric threshold coefficient of variation; AUC = area under the receiver operating characteristic curve; SE = standard error; and CI = 5–95% confidence intervals.