Table 3.
Performance of Laguna ONhE, OCT, and perimetry indices.
| GDF | RNFLT | Rim Area | OCT-C/D | MD | PSDr | TCV | |
|---|---|---|---|---|---|---|---|
| AUC susp. | 0.932 | 0.709 | 0.827 | 0.834 | 0.687 | 0.651 | 0.718 |
| AUC conf. | 0.986 | 0.944 | 0.968 | 0.958 | 0.985 | 0.98 | 0.981 |
| SE susp. | 0.013 | 0.0303 | 0.025 | 0.0223 | 0.0297 | 0.0311 | 0.029 |
| SE conf. | 0.00437 | 0.0107 | 0.00877 | 0.00867 | 0.00316 | 0.00432 | 0.00391 |
| CI susp. | 0.908–0.951 | 0.670–0.746 | 0.794–0.857 | 0.801–0.864 | 0.647–0.725 | 0.611–0.690 | 0.679–0.754 |
| CI conf. | 0.974–0.993 | 0.925–0.960 | 0.952–0.979 | 0.940–0.971 | 0.973–0.993 | 0.966–0.989 | 0.968–0.990 |
| GDF | RNFLT | Rim Area | OCT-C/D | MD | PSDr | ||
| RNFLT susp. | p < 0.0001 | ||||||
| RNFLT conf. | p = 0.0002 | ||||||
| RimArea susp. | p < 0.0001 | p = 0.0002 | |||||
| Rim Area conf. | p = 0.0635 | p = 0.0490 | |||||
| OCT-C/D susp. | p < 0.0001 | p = 0.0001 | p = 0.7755 | ||||
| OCT-C/D conf. | p = 0.0019 | p = 0.2691 | p = 0.1642 | ||||
| MD susp. | p < 0.0001 | p = 0.5917 | p = 0.0004 | p = 0.0001 | |||
| MD conf. | p = 0.8630 | p = 0.0002 | p = 0.0636 | p = 0.0025 | |||
| PSDr susp. | p < 0.0001 | p = 0.1429 | p < 0.0001 | p < 0.0001 | p = 0.2399 | ||
| PSDr conf. | p = 0.2847 | p = 0.0015 | p = 0.2264 | p = 0.0199 | p = 0.2146 | ||
| TCV susp. | p < 0.0001 | p = 0.8057 | p = 0.0022 | p = 0.0008 | p = 0.2796 | p = 0.0050 | |
| TCV conf. | p = 0.3720 | p = 0.0008 | p = 0.1663 | p = 0.0106 | p = 0.2885 | p = 0.6232 |
GDF = Laguna ONhE globin distribution factor; RNFLT = OCT retina nerve fiver layer thickness; OCT-C/D = OCT vertical cup/disc ratio; MD = perimetric mean defect or deviation; PSDr = perimetric pattern standard deviation or square root of loss variance rectified; TCV = perimetric threshold coefficient of variation; AUC = area under the receiver operating characteristic curve; SE = standard error; and CI = 5–95% confidence intervals.