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. 2021 Jul 22;10(15):3231. doi: 10.3390/jcm10153231

Table 4.

Performance of the combination of Laguna ONhE and Cirrus-OCT variables and perimetric variables between reference and confirmed (conf.) and suspect (susp.) glaucoma cases.

GDF and TCV GDF and PSDr Rim Area and PSDr OCT-C/D and PSDr RNFLT and PSDr
AUC conf. 0.995 0.995 0.988 0.988 0.987
AUC susp 0.935 0.932 0.843 0.847 0.742
SE conf. 0.0021 0.0021 0.0049 0.0035 0.0033
SE susp. 0.013 0.015 0.024 0.022 0.029
CI conf. 0.987–0.999 0.987–0.999 0.977–0.995 0.977–0.995 0.976–0.994
CI susp 0.912–0.954 0.908–0.951 0.810–0.871 0.815–0.876 0.704–0.77
GDF and TCV GDF and PSDr Rim Area and PSDr OCT-C/D and PSDr
GDF and PSDr conf. p = 0.695
GDF and PSDr susp. p = 0.323
Rim Area and PSDr conf. p = 0.187 p = 0.195
Rim Area and PSDr susp. p < 0.0001 p = 0.0002
OCT-C/D and PSDr conf. p = 0.060 p = 0.064 p = 0.8728
OCT-C/D and PSDr susp. p < 0.0001 p < 0.0001 p = 0.839
RNFLT and PSDr conf. p = 0.036 p = 0.037 p = 0.852 p = 0.859
RNFLT and PSDr susp. p < 0.0001 p < 0.0001 p = 0.0005 p = 0.0001

GDF = Laguna ONhE globin distribution factor; RNFLT = OCT retina nerve fiver layer thickness; OCT-C/D = OCT vertical cup/disc ratio; MD = perimetric mean defect or deviation; PSDr = perimetric pattern standard deviation or square root of loss variance rectified; TCV = perimetric threshold coefficient of variation; AUC = area under the receiver operating characteristic curve; SE = standard error; and CI = 5–95% confidence intervals.