Skip to main content
. 2021 Jul 28;26(15):4563. doi: 10.3390/molecules26154563

Table 1.

The friedelane triterpenes isolated from Maytenus.

No. Name R1 R2 R3 R4 R5 R6 R7 R8 Type Ref.
1 Pristimerin H H COOMe H H - - - A1 [16]
2 15α-hydroxy-21-keto-pristimerine α-OH H COOMe =O H - - - A1 [17]
3 2,3,22β-trihydroxy-24,29-dinor-1,3,5(10),7-friedelatetraene-6,21-dione-23-al OH OH CHO H =O β-OH - - A2 [18]
4 2,22β-dihydroxyl-3-methoxy-24,29-dinor-1,3,5(10),7-friedelatetraene-6,21-dione OH OH CH3 H =O β-OH - - A2 [18]
5 2,3,22β-triihydroxy-23,24,29-trinor-1,3,5(10),7-friedelatetr aene-6,21-dione OH OH H H =O β-OH - - A2 [18]
6 2,22β-dihydroxyl-3-methoxy-24,29-dinor-1,3,5(10),7-friedelatetraene-6,21-dione OH OCH3 CH3 H =O β-OH - - A2 [18]
7 2,3,22β-trihydroxy-24,29-dinor-1,3,5(10)–friedelatetraene -6,21-dione OH CH3 =O H H H =O β-OH A3 [18]
8 2,15α,22β-trihydroxy-3-methoxy-24,29-dinor-1,3, 5(10)-friedelatriene-21-one OCH3 CH3 H H α-OH H =O β-OH A3 [18]
9 3,22β-dihydroxy-24,29-dinor-l(10)-3,5-friedelatriene-2,7,21-trione =O β-OH =O H - - - - A4 [18]
10 3,22β-dihydroxy-24,29-dinor-l(10),3,5–friedelatriene-21-one H β-OH =O H - - - - A4 [18]
11 2,3,22β-trihydroxy-24,29-dinor-25(9→8)-1,3,5(10),7-friedelatetraene-21-one-23-al β-OH - - - - - - - A5 [18]
12 23-oxo-iso-tingenone H - - - - - - - A5 [19]
13 (8S)-7,8-dihydro-7-oxo-tingenoe =O H =O H - - - - A4 [19]
14 (7S, 8S)-7-hydroxy-7,8-dihydro-tingenone α-OH H =O H - - - - A4 [19]
15 (8S)-7,8-dihydro-6-oxo-tingenol OH CH3 =O H H H =O H A3 [19]
16 23-nor-6-oxo-tingenol OH OH H H =O H - - A2 [19]
17 28-hydroxy-friedelane-1,3-dione =O H H H CH2OH CH3 CH3 - A6 [20]
18 Macrocarpin A OH CHO =O H H COOMe H H A3 [21]
19 Macrocarpin B OH OH COOH H =O β-OH - - A2 [21]
20 Macrocarpin C OH OCH3 COOH H =O β-OH - - A2 [21]
21 Macrocarpin D α-OH β-OH =O H - - - - A4 [21]
22 Maytenfolone - - - - - - - - A7 [22]
23 6-oxo-iguesterol - - - - - - - - A8 [12]
24 6-oxo-tingenol OH OH CH3 H =O H - - A2 [12]
25 3-O-methoxy-6-oxo-tingenol OH OCH3 CH3 H =O H - - A2 [12]
26 Blepharotriol OH OH OH COOMe H H - - A2 [23]
27 6-deoxoblepharodol OH CH3 H H H COOMe H H A3 [23]
28 Isoblepharodol OH CH3 H =O H COOMe H H A3 [23]
29 7-oxo-blepharodol OH CH3 =O =O H COOMe H H A3 [23]
30 15α-hydroxy-tingenone α-OH H H =O H - - - A1 [24]
31 15-dihydro-pristimerin - - - - - - - - A9 [24]
32 Vitideasin α-COOCH3 H - - - - - - A10 [24]
33 20β-hydroxy-scutione α-OH =O - - - - - - A10 [24]
34 7-oxo-7,8-dihydro-scutione - - - - - - - - A11 [25]
35 6,23-dioxo-7,8-dihydro-pristimerol-23-oic Acid OH COOH =O H H COOMe H H A3 [25]
36 23-nor-blepharodol OH H =O H H COOMe H H A3 [25]
37 3-methoxy-6-oxo-tingenol-23-oic Acid OH OCH3 COOH H =O H - - A2 [25]
38 Retusonine - - - - - - - - A12 [25]
39 21-Oxopristimerine H H COOMe =O H - - - A1 [25]
40 3-O-methyl-6-oxo-pristimerol OH OCH3 CH3 COOMe H H - - A2 [26]
41 3β,24-epoxy-2α,3α-dihydroxy-D:A-friedooleanan-29-oic acid methyl ester OH OH H - - - - - A13 [27]
42 2α-acetoxy-3β,24-epoxy-3α-hydroxy- D:A-friedooleanan-29-oic acid methyl ester OAc OH H - - - - - A13 [27]
43 3α-hydroxy- D:A-friedooleanan-28-oic acid α-OH H H COOH H - - - A14 [27]
44 3-oxo-D:A-friedooleanan-28,30-olide - - - - - - - - A15 [27]
45 3β,11β-dihydroxyfriedelane β-OH β-OH H CH3 H - - - A14 [28]
46 3,4-seco-friedelan-3,11β-olide - - - - - - - - A16 [28]
47 (16β)-16-hydroxy-pristimerin H β-OH COOMe H H - - - A1 [29]
48 12,16-dihydroxyfriedelan-3-one H H α-OH β-OH CH3 CH3 CH3 - A6 [30]
49 3β,24β-epoxy-29-methoxy-2α,3α,6α-trihydroxy-D:A-friedelane OH OH β-OH - - - - - A13 [31]
49a 3β,24β-epoxy-29-methoxy-2α,3α,6α-triacetoxy-D:A-friedelane OAc OAc β-OAc - - - - - A13 [31]
50 Friedel-1-en-3,16-dione - - - - - - - - A17 [32]
51 1α,29-dihydroxyfriedelan-3-one α-OH H H H CH3 CH3 CH2OH - A6 [32]
52 16β,28,29-trihydroxyfriedelan-3-one H H H β-OH CH2OH CH3 CH2OH - A6 [32]
53 Dispemroquinone =O H H COOMe - - - - A5 [33]
54 Scutione H =O - - - - - - A10 [34]
55 Zeylasterone OH OH COOH COOMe H H - - A2 [35]
56 Demethylzeylasterone OH OH COOH COOH H H - - A2 [35]
57 3,15-dioxo-21-hydroxy friedelane =O H =O CH3 α-OH - - - A14 [36]
58 Maytenfoliol H H H H CH2OH CH2OH CH3 - A6 [37]
59 Cangorosin A H - - - - - - - A18 [38]
60 Atropcangorosin A H(atropisomer of 7-bu) - - - - - - - A18 [38]
61 Dihydroatropcangorosin A 6′,7′-dihydro derivative of 8-BU - - - - - - - A18 [38]
62 Cangorosin B - - - - - - - - A19 [38]
63 Umbellatin α α-Me - - - - - - - A20 [39]
64 Umbeilatin β β-Me - - - - - - - A20 [39]
65 Tiscutin A - - - - - - - - A21 [40]
66 Triscutin B - - - - - - - - A22 [40]
67 Xuxuarine Eα - - - - - - - - A23 [41]
68 Scutionin αB - - - - - - - - A24 [42]
69 6′,7′-dihydro-scutionin αB H - - - - - - - A25 [42]
70 6′β-methoxy-6′,7′dihydro-scutionin αB OCH3 - - - - - - - A25 [42]