Table 2.
Morphological Data | Nephron Segments | Pathophysiological Mechanism |
---|---|---|
Epithelial necrosis | Proximal tubules | Direct viral infections, hemodynamic disorders, rhabdomyolysis |
Cellular debris | Lumen of tubules | |
Myoglobin | Tubules | Rhabdomyolysis |
Corona-like viruses | Podocytes, tubules | Direct viral infections |
Isometric vacuolization | Tubules | |
Loss of brush border, flattening, damage | Tubules | Direct viral infections, cytokine storm |
Swelling of endothelial cells | Glomerulus |