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. 2021 Jul 28;22(15):8081. doi: 10.3390/ijms22158081

Table 2.

The most common histopathological observations in COVID-19.

Morphological Data Nephron Segments Pathophysiological Mechanism
Epithelial necrosis Proximal tubules Direct viral infections, hemodynamic disorders, rhabdomyolysis
Cellular debris Lumen of tubules
Myoglobin Tubules Rhabdomyolysis
Corona-like viruses Podocytes, tubules Direct viral infections
Isometric vacuolization Tubules
Loss of brush border, flattening, damage Tubules Direct viral infections, cytokine storm
Swelling of endothelial cells Glomerulus