Figure 1.

Microbiota-metabolites and inflammatory markers in preterm birth. O: Oral; G: Gut; B: Blood; U: Urine; V: Vagina; C: Cervix; P: Placenta; A: Amniotic fluid. TMA: Trimethylamine, TMAO: Trimethylamine N-oxide; IL: Interleukin; TNF: Tumor necrosis factor; MMP: Matrix metalloproteinase; CCL: C-C motif chemokine ligand; CXCL: C-X-C motif chemokine; PTGDS2: Prostaglandin D2 synthase; OXTR: Oxytocin receptor; CX: Connexin; NFkB: Nuclear factor-kappa B; COX: Cyclooxygenase; PGDH: Prostaglandin dehydrogenase. Dashed lines indicate several steps, ↓ decreased, ↑ increased level. Location followed by color code.