Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
NMMII might induce positive feedback loops. When ATPase activity of NMMII is inhibited, it can release GEFs of the Dbl family, which are likely to further inhibit NMMII via activation of the Rac1-PAK pathway. It is not clear which state of NMMII (active or inactive ATPase activity) can induce the release of active MyoGEF. Active MyoGEF can stimulate NMMII via activation of ROCK.
