Table 2.

Cardiac-resident macrophage clusters in homeostasis by transcriptomic profile.

Cell Type	Cluster	Signature Genes	Origin	Functions
Cardiac resident macrophages	scRNAseq 1	Timd4 Folr2 Lyve1 CD163 Igf1	Embryonic	Homeostatic Angiogenesis Endocytosis Lysosomal
Cardiac resident macrophages	scRNAseq 2	MHC II F4/80 Cx3xr1 CD14	Embryonic	Translational Ribosomal Antigen presentation
Cardiac resident macrophages	scRNAseq 3	Ccr2 CD64	Monocytes	Classical inflammatory pathways
Cardiac resident macrophages	scRNAseq 4	Ifit1 Ifit3 Irf7	Monocytes	Classical inflammatory pathways Interferon response