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. 2021 Jul 28;22(15):8065. doi: 10.3390/ijms22158065

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ROC curve analysis of exosomes versus cardiovascular clinical manifestation. Receiver operating characteristic (ROC) curve analysis was used to evaluate the ability of exosome to discriminate between STEMI (overall) and CCS patients (a–e) and between OHCA-STEMI and uncomplicated STEMI (f,g) in terms of dimension (mode) (a), GPIIb (b–f), VE-cadherin (c), ceruloplasmin (d), transthyretin (e) and/or PLP1 (g). Areas under the curve (AUCs), p values for AUC differences, cut-off values, sensitivity, and specificity are reported.