Table 1.
Baseline characteristics of the study population
| Characteristics | All patients n = 795 |
|---|---|
| Age (years) | 81.0 (77.0; 85.0) |
| Male sex (%) | 330 (41.5%) |
| Body mass index (kg/m2) | 27.3 (24.1; 30.9) |
| Logistic EuroSCORE | 18.5 (12.8; 29.0) |
| STS score risk of mortality | 8.1 (5.4; 12.3) |
| eGFR (mL/min per 1.73 m2) | 53 (39; 69) |
| NYHA class, number (%) | |
| II | 124 (15.6%) |
| III | 494 (62.1%) |
| IV | 132 (16.6%) |
| Diabetes mellitus , number (%) | 345 (43.4%) |
| Hypertension, number (%) | 717 (90.2%) |
| Coronary artery disease, number (%) | 368 (46.3%) |
| Previous MI, number (%) | 98 (12.3%) |
| Previous stroke, number (%) | 63 (7.9%) |
| Peripheral artery disease, number (%) | 90 (11.3%) |
| COPD, number (%) | 289 (36.4%) |
| Atrial fibrillation, number (%) | 274 (34.5%) |
| Previous CABG, number (%) | 117 (14.7%) |
| Previous PCI, number (%) | 182 (22.9%) |
| Grip strength | 18.0 (13.0; 24.5) |
| Gait speed | 7.0 (6.0; 9.0) |
| Echocardiographic findings | |
| LVEF < 55%, number (%) | 314 (39.5%) |
| Peak velocity baseline, m/s | 4.2 (3.7; 4.7) |
| Maximum gradient, mm Hg | 71 (56;88) |
| Mean gradient, mm Hg | 44 (35;56) |
| AVA, cm2 | 0.6 (0.5;0.8) |
| Systolic PAP > 60 mm Hg, number (%) | 291 (36.6%) |
| MR ≥ 2 - no. (%) | 89 (11.2%) |
All values are given in median (interquartile range) or number (%) unless otherwise stated.
AVA, aortic valve area, CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; PAP, pulmonary artery pressure; LVEF, left-ventricular ejection fraction; MR, mitral regurgitation; NYHA, New York Heart Association; PCI, percutaneous coronary intervention; STS, Society of Thoracic Surgeons.