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. 2021 Jun 6;29(7):751–763. doi: 10.1016/j.jsps.2021.05.007

Table 1.

Summary of the most important biological actions of the plant.

Part of the plant The active extract, fraction or pure compund The biological effect or action Mechanism of action or target Reference
Roots Ethanol extract and its purified persicaline compound. Antioxidant. Not identified. (Farag et al., 2018).
Roots. Benzyl isothiocyante and its hydroxyl and methoxy derivatives Antimicrobial Suppress the bacterial redox system by damaging the membrane potential. (Abd El Kader et al., 2017c).
Fruits Fruits extract Antimicrobial activity for Streptococcus mutans. Inhibits cariogenic bacteria growth and acid production. (Al Bratty et al., 2020).
Roots Essential oils Antimicrobial comparable to that of chlorhexidine digluconate. Inhibits cariogenic bacteria growth and acid production. (Khan et al., 2020).
Not specified. Apigenin, luteolin, astragalin and kaempferol-3-O-rhamnoside from alcoholic extract. Anti-MRSA [Methicillin-resistant Staphylococcus aureus]. Not identified (Ghoneim et al., 2019).
Twigs Methanol extract. Wound healing effect. By antioxidant and antimicrobial properties. (Tatke et al., 2017)
Roots Aqueous extract. Antiprotozoal activity. Not identified. (El-Bali et al., 2020).
Leaves Ethyl acetate extract. Anti-inflammatory. May be due to high concentration of flavonoids. (Rajesh et al., 2010).
Sticks crude ethanol extract and its ethyl acetate fraction. Anti-inflammatory. May be due to high concentration of flavonoids. (Ibrahim et al., 2011b).
Roots Crude hydro-alcholic extract Analgesic activity. Not identified. (Hooda and Pal, 2017).
Twigs a lyophilized decoction Antiulcer Not identified. (Sanogo et al., 1999).
Stems a lyophilized decoction Antiulcer Not identified. (Monforte et al., 2001).
Stems Total extract Antidepressant Not identified. (Monforte et al., 2002).
Roots Aqueous extract. Hypoglycemic and hypolipidemic. Not identified. (Khan et al., 2014).
Twigs Powder. Hypoglycemic and hypolipidemic. Not identified. (El Rabey et al., 2017).
Leaves Aqueous extract. Hypoglycemic and hypolipidemic. Not identified. (Haddad El Rabey et al., 2018).
Fruits Ethanol extract. Anticancer. Cytotoxic effect. (Al Bratty et al., 2020).
Bark Petroleum ether extract Anticancer Cytotoxic effect. (Ibrahim et al., 2011a).
The aerial parts Aqueous extract May help against COVID-19 COVID-19 main protease inhibitor. (Owis et al., 2020).