Figure 1.
Illustration of RCA synthesis of nanocomposite gels containing an expression vector. (a) DNA-modified silica nanoparticles (SiNP) and DNA-modified carbon nanotubes (CNT) are used in different ratios for rolling circle amplification (RCA) interweaving a protein-coding plasmid. Proportions of SiNP (80 nm diameter), CNT (1 µm × 0.83 nm) and coding plasmid (6200 bp) are not sketched to scale. Gels were synthesized in different formats, either in microliter volumes termed as bulk hydrogels (b), or inside water-in-oil emulsion droplets (c) to yield microgels.