ACPA |
anti-citrullinated protein antibody |
AS |
ankylosing spondylitis |
CCL |
C-C motif chemokine ligand |
CXCL |
C-X-C motif chemokine ligand |
DMARD |
disease-modifying antirheumatic drug |
ERA |
enthesitis-related arthritis |
FcγR |
Fcγ receptor |
GM-CSF |
granulocyte-macrophage colony-stimulating factor |
HIF |
hypoxia-inducible factor |
IC |
immunocomplex |
ICAM-1 |
intracellular adhesion molecule 1 |
IL |
interleukin |
ILAR |
International League of Associations for Rheumatology |
IFN |
Interferon |
IP-10 |
IFNγ inducible protein 10 |
IRAK |
IL-1R-activating kinase |
IRF |
interferon regulatory factor |
JAK |
Janus kinase |
JIA |
juvenile idiopathic arthritis |
LPS |
lipopolysaccharide |
MAPK |
mitogen-activated protein kinase |
MAS |
macrophage activation syndrome |
MCP-1 |
monocyte chemoattractant protein-1 |
MMP |
matrix metalloproteinases |
Mφ |
macrophage |
Mo |
monocyte |
MTX |
methotrexate |
MyD88 |
myeloid differentiation primary response protein 88 |
NFκB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NK |
natural killer |
NLRP3 |
NOD-, LRR-, and pyrin domain-containing protein 3 |
PBMCs |
peripheral blood mononuclear cells |
PPARγ |
peroxisome proliferator-activated receptor gamma |
RA |
rheumatoid arthritis |
RANTES |
regulated upon activation, normal T cell expressed and presumably secreted |
RF |
rheumatoid factor |
RANK |
receptor activator of NFκB |
RANKL |
RANK ligand |
SF |
synovial fluid |
sJIA |
systemic onset JIA |
SOCS |
suppressor of cytokine signaling |
STAT |
signal transducer and activator of transcription |
TGFβ |
transforming growth factor beta |
Th1 |
type 1 helper T cells |
Th17 |
type 17 helper T cells |
TLR |
Toll-like receptor |
TNF |
tumor necrosis factor |
TREM |
triggering receptor expressed on myeloid cells |
TRAF |
TNF receptor associated factor |
VEGF |
vascular endothelial growth factor |