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. 2021 Jul 31;22(15):8267. doi: 10.3390/ijms22158267

Figure 2.

Figure 2

17,18-EEQ or 19,20-EDP combined with t-TUCB delivered via mini osmotic pump decreased the fasting glucose and serum TG levels in diet-induced obesity. Male C57BL/6J mice fed with a high-fat diet (45% kcal from fat) were treated with t-TUCB (3 mg/kg/day) alone or combined with 19,20-EDP (0.05 mg/kg/day) (T + EDP) or 17,18-EEQ (0.05 mg/kg/day) (T + EEQ) by osmotic minipump implantation for 6 weeks, as described. Insulin tolerance test and the area under the curve (AUC) (A,B), oral glucose tolerance test and the area under the curve (C,D), fasting glucose levels (E), serum insulin (F), serum TC (G), NEFA (H), and TG levels (I) after 6 weeks of implantation are shown. Data = the mean ± SEM (n = 5–6). *, ** = p < 0.05 and p < 0.01 compared to the controls, respectively.