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Neuroprotective effects on SH-SY5Y cells of different concentrations of curcumin and curcumin–coumarin hybrid analogues 14 and 16 and their nanoparticle formulations (NC). Each value is the mean ± s.e.m of at least 5 experiments. # p < 0.0001 versus the control group (without H2O2 treatment), ** p < 0.005, *** p < 0.001, **** p < 0.0001 versus cells treated with H2O2.
