Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 2;22(15):8300. doi: 10.3390/ijms22158300

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Knockdown of miR-7-5p enhanced ΔΨm. ΔΨm was visualized by 2 µM JC-1 after the miR-7-5p knockdown. JC-1 is a fluorescent probe that is localized mitochondria and is changed fluorescence according to the membrane potential. (A) HeLa CRR cells siN.C. treatment. (B) HeLa CRR cell simiR-7-5p treatment. (C) SAS CRR cells siN.C. treatment. (D) SAS CRR cell simiR-7-5p treatment. (E) Relative JC-1 intensity (HeLa CRR N.C.: n = 11, HeLa CRR simiR-7-5p: n = 10, SAS CRR N.C.: n = 51, SAS CRR simiR-7-5p: n = 25). **: p < 0.01 using Student’s t test. Knockdown of miR-7-5p significantly increased ΔΨm.