Table 3.
Comparisons of AUCs, IDI, and NRI for predicting good CPC at 1 month using CT methods and TCD-VMR test.
AUC | Difference in AUC | Standard Error of Difference in AUC | 95% CI of Difference in AUC | p-Value (Difference in AUCs) | Relative IDI (%) | p-Value (Relative IDI) | NRI | p-Value (NRI) | Valid n | |
---|---|---|---|---|---|---|---|---|---|---|
GWR ≥ 1.17 | 0.614 | 0.205 | 0.043 | 0.121–0.289 | <0.001 | Ref. | Ref. | 115 | ||
GWR ≥ 1.17 + VMR ≥ 30.3 | 0.819 | 0.28 | <0.001 | 0.36 | 0.001 | 115 | ||||
ASPECTS-b ≥ 7 | 0.666 | 0.170 | 0.041 | 0.090–0.250 | <0.001 | Ref. | Ref. | 115 | ||
ASPECTS-b ≥ 7 + VMR ≥ 30.3 | 0.837 | 0.24 | <0.001 | 0.25 | 0.018 | 115 | ||||
GWR ≥ 1.17 + ASPECTS-b ≥ 7 | 0.711 | 0.131 | 0.040 | 0.052–0.209 | 0.001 | Ref. | Ref. | 115 | ||
GWR ≥ 1.17 + ASPECTS-b ≥ 7 + VMR ≥ 30.3 | 0.841 | 0.22 | <0.001 | 0.20 | 0.041 | 115 |
Abbreviations: ASPECTS-b, bilateral Alberta stroke program early computed tomography score; AUC, area under the receiver operating characteristics curve; CI, confidential interval; CPC, cerebral performance category; GWR, gray-to-white matter ratio; IDI, integrated discrimination improvement; NRI, net reclassification improvement; TCD, transcranial Doppler; VMR, vasomotor reactivity.