(a) Dependences of Em0 on percentage of inactivation of inward K+ channels at SD = 40% (n = 5) and (b) AAP, (c) Δtth, and (d) ΔTth in the control (no inactivation of K+ channels, SD = 0%), the “0% + 40%” variant (no inactivation of K+ channels, SD = 40%), and the “14% + 40%” variant (14% of K+ channels inactivation; SD = 40%). *, the “14% + 40%” variant was significantly differed from the control. #, the “14% + 40%” variant was significantly differed from the “0% + 40%” variant. The rate of the T decrease was 0.5 °C min−1. Averaged parameters (AAP, Δtth, and ΔTth) shown in Figure 8b–d were calculated on the basis of 25 repeated simulations.