Table 3.

Effect of the glucose-based macrocycles (1 or 2) in Michael addition of β-nitrostyrene (14) and diethyl acetamidomalonate (15).

Entry	Catalyst	Time, h	Yield, % a	ee, % b
1	1a	72	49	42
2	1b	48	42	28
3	1c	120	33	21
4	2a	3	70	99 c
5	2b	22	58	38
6	2c	120	36	15

^a Isolated by preparative TLC; ^b Determined by chiral HPLC; ^c See Ref. [65].