Table 3.
Antibacterial activity of the variant peptides shown as MIC (MBC) in µM tested against 12 clinical Salmonella isolates.
| Isolate Code | Kn2-5R | Kn2-5R-NH2 | dKn2-5R-NH2 | 2F-Kn2-5R-NH2 |
|---|---|---|---|---|
| 5 | 8 (8) | 4 (4) | 8 (8) | 4 (4) |
| 7 | 8 (8) | 4 (4) | 8 (8) | 4 (4) |
| 11 | 8 (8) | 4 (4) | 8 (8) | 4 (4) |
| 18 | 8 (8) | 4 (4) | 8 (8) | 8 (8) |
| 26 | 8 (8) | 4 (4) | 8 (8) | 8 (8) |
| 27 | 8 (8) | 4 (4) | 4 (4) | 8 (8) |
| 55 | 8 (8) | 4 (4) | 4 (4) | 8 (8) |
| 61 | 8 (8) | 4 (4) | 4 (4) | 4 (4) |
| 69 | 8 (8) | 4 (4) | 4 (4) | 4 (4) |
| 76 | 8 (8) | 4 (4) | 8 (8) | 8 (8) |
| 78 | 8 (8) | 4 (4) | 8 (8) | 8 (8) |
| 107 | 8 (8) | 4 (4) | 4 (4) | 4 (4) |
| GM | 8 (8) | 4 (4) | 5.99 (5.99) | 5.66 (5.66) |
| MBC/MIC ratio | 1 | 1 | 1 | 1 |
MIC: minimal inhibitory concentration. MBC: minimal bactericidal concentration. GM: geometric mean.