Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 5;153(9):e202112872. doi: 10.1085/jgp.202112872

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Abderemane-Ali et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Figure 1. — Pitohui and poison frog Na_V1.4 channels are BTX sensitive.(a, c, e, and g) Exemplar current recordings for Pum Na_V1.4 (a), Hs Na_V1.4 (c), Pt Na_V1.4 (e), and Dt Na_V1.4 (g) expressed in HEK293 cells in the absence (left) or presence (right) of 10 µM BTX. Trace at 0 mV is highlighted in each panel. Currents were evoked with the shown multistep depolarization protocol (inset in a). (b, d, f, and h) G-V relationships in the presence or absence of 10 µM BTX for Pum Na_V1.4 (black diamonds), +BTX (orange diamonds; b), Hs Na_V1.4 (black circles), +BTX (purple circles; d), Pt Na_V1.4 (white circles), +BTX (dark orange circles; f), and Dt Na_V1.4 (white squares), +BTX (blue squares; h). (i) Exemplar current recordings from mock-transfected HEK293 cells using the protocol from a.