RTK	Receptor tyrosine kinase
TGF	Transforming growth factor beta
CAF	Cancer-associated fibroblast
PDAC	Pancreatic ductal adenocarcinoma
PDGF	Platelet-derived growth factor
PDGFR	Platelet-derived growth factor receptor
CNS	Central nervous system
MAPK	Mitogen-activated protein kinase
PI3K	Phosphoinositide 3-kinases
ECM	Extracellular matrix
VEGF	Vascular endothelial growth factor
COX-2	Cyclooxygenase-2
NSCLC	Non-small cell lung cancer
OS	Overall survival
PFS	Progression-free survival
IGF1R	Insulinlike growth factor 1 receptor
LIF	Leukemia inhibitory factor
JAK/STAT	Janus kinases (JAKs), signal transducer and activator of transcription proteins (STAT)
SMAD4	Mothers against decapentaplegic homolog 4