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. 2021 Jul 31;2(3):100687. doi: 10.1016/j.xpro.2021.100687

Figure 4.

Figure 4

Etomoxir concentration-response curve in permeabilized cells

(A) Representative respirometry trace in permeabilized HepG2 cells offered palmitoyl CoA and carnitine with malate and varying concentrations of etomoxir.

(B) Concentration-response curve of FCCP-stimulated respiration in permeabilized HepG2 cells (as in A) in response to increasing concentrations of etomoxir. Red lines identify the EC50 value (9.2 nM) for etomoxir from this particular experiment. When not visible, error bars are obscured by the symbol. Data are presented as mean ± SEM (n=5 technical replicates).