Table 1.
Total Cohort | No Sarcopenia | Sarcopenia | p-Value * | |
---|---|---|---|---|
(n = 676) | (n = 575) | (n = 101) | ||
Characteristics | ||||
Age, years | 71 (64–78) | 70 (61–77) | 78 (73–84) | <0.001 |
Body mass index, kg/m² | 23.4 (21.3–26.0) | 23.7 (21.7–26.4) | 21.7 (19.7–24.0) | <0.001 |
Male sex | 458 (68) | 399 (69) | 59 (58) | 0.037 |
Etiology | 0.032 | |||
Hepatitis B virus | 99 (15) | 92 (16) | 7 (7) | |
Hepatitis C virus | 212 (31) | 171 (30) | 41 (41) | |
Alcohol-related | 110 (16) | 96 (17) | 14 (14) | |
Others | 255 (38) | 216 (38) | 39 (39) | |
Liver cirrhosis | 421 (62) | 347 (60) | 74 (73) | 0.014 |
Child–Pugh class † | 0.800 | |||
A | 302 (72) | 251 (72) | 51 (69) | |
B | 97 (23) | 78 (23) | 19 (26) | |
C | 22 (5) | 18 (5) | 4 (5) | |
Hepatocellular carcinoma | 425 (63) | 352 (61) | 73 (72) | 0.034 |
SARC-F components | ||||
Strength | <0.001 | |||
None (0) | 577 (85) | 508 (88) | 69 (68) | |
Some (1) | 77 (11) | 49 (9) | 28 (28) | |
A lot or unable (2) | 22 (3) | 18 (3) | 4 (4) | |
Assistance in walking | <0.001 | |||
None (0) | 611 (90) | 534 (93) | 77 (76) | |
Some (1) | 58 (9) | 36 (6) | 22 (22) | |
A lot, use aids, or unable (2) | 7 (1) | 5 (1) | 2 (2) | |
Rising from a chair | <0.001 | |||
None (0) | 595 (88) | 522 (91) | 73 (72) | |
Some (1) | 78 (12) | 51 (9) | 27 (27) | |
A lot or unable without help (2) | 3 (0) | 2 (0) | 1 (1) | |
Climbing stairs | <0.001 | |||
None (0) | 529 (78) | 468 (81) | 61 (60) | |
Some (1) | 126 (19) | 93 (16) | 33 (33) | |
A lot or unable (2) | 21 (3) | 14 (2) | 7 (7) | |
Falls | <0.001 | |||
None (0) | 551 (82) | 487 (85) | 64 (63) | |
1–3 falls (1) | 120 (18) | 84 (15) | 36 (36) | |
4 or more falls (2) | 5 (1) | 4 (1) | 1 (1) |
Values are presented as number (percentage) or median (interquartile range). † Patients with cirrhosis were evaluated. * The chi-square test for categorical variables or Mann–Whitney U test for continuous variables were used to compare clinical characteristics between the two groups.