T1D	type 1 diabetes
T2D	type 2 diabetes
IL-1β	interleukin-1 beta
TNF	tumor necrosis factor
IFN	interferon
NF-κB	nuclear factor kappa B
ROS	reactive oxygen species
NGF	nerve growth factor
TLR	toll-like-receptor
ERAD	endoplasmic reticulum-associated degradation
JNK	c-Jun N-terminal kinase
siRNA	small interfering RNA
ER	endoplasmic reticulum
LC-MS/MS	liquid chromatography-tandem mass spectrometry
TMT	tandem mass tags
INS-1E	insulin-producing β-cell line
FDR	false discovery rate
mRNA	messenger RNA
ADAM	disintegrin and metalloproteinase domain-containing protein
CON	un-transfected control β-cells
SC	scrambled siRNA transfected control β-cells
DMT1-KD	control β-cells transfected with three different siRNAs targeting DMT1
CON-IL	un-transfected β-cells exposed to IL-1β
SC-IL	scrambled siRNA transfected β-cells exposed to IL-1β
DMT1-KD-IL	β-cells exposed to IL-1β transfected with three different siRNAs targeting DMT1