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CD38-targeting DFMT system depicted using DARA-MORF1 as the bispecific engager and HSA-(MORF2)y as the crosslinking effector molecule. DFMT is a two-step process involving step (1): specific antigen engagement by the bispecific engager followed by step (2): receptor crosslinking via the effector nanoconjugate. Crosslinking occurs via hybridization of complementary morpholino oligonucleotides conjugated to the bispecific engager and effector molecules.
