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. 2021 Jul 29;22(15):8127. doi: 10.3390/ijms22158127

Table 4.

Biomarkers used to diagnose different stages of cancers (Cervical cancer).

Biomarker Normal CIN1 CIN2 CIN3 I II III IV Ref
MiB-1 10%> >10% - - >71% >I >II,I High [140]
CDC6 90% 38% - 24% - - 70% - [141]
CD44 - - - - High <I <I,II <I,II,III [142]
CK7 Positive - - - - - negative Negative [143]
hMSH2 - - - - - - 54.3% - [71]
Ki-67 20%> 22.6% 82.1% 88.6% - - 100% - [144]
p16 >10% 10.4% 84.5% 90.5% - - 91.3% - [144]
SSC-Ag - - - - 24% 53% 75% 90% [145]
MCM3 negative 4–6% - - - - 18% - [141]
p63 100% 100% - - 30% - - 10% [146]
p53 <10% 10% 50% 71% - - - - [146]