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Potential anti-aging effects of resveratrol in the kidney. Resveratrol may mediate anti-aging effects in the kidney through the regulation of three main signaling pathways, SIRT1, AMPK, and NF-κB, which ultimately suppress pathological conditions, such as telomere shortening, inflammation, oxidative stress, fibrosis, mitochondrial dysfunction, autophagy dysfunction, ER stress, and DNA damage, in the kidney. Arrow means activation, and ‘T’ arrow means inhibition.
