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. 2021 Jul 29;22(15):8148. doi: 10.3390/ijms22158148

Figure 1.

Figure 1

The structure of a mature eukaryotic mRNA and a modified mRNA. The anti-reverse cap analogs (ARCAs) and modified nucleotides such as 5-methyluridine (5mU), 5-methylcytidine (5mC), pseudouridine (ψU), N6-methyladenosine (6mA), N1-methylpseudouridine (1mψU), 5-methoxyuridine (5moU), 2-thiouridine (2TU), 5-iodouridine (5IU), and 5-iodocytidine (5IC) are usually used in modified mRNA.