Table 3.

Fetal weights, growth parameters, and uteroplacental characteristics assessed at necropsy (130 dGA).

	CON RNAi	CSH RNAi	% Change	p-Value
	(n = 4)	(n = 4)
Crown-rump length, cm	49.98 ± 1.67	45.73 ± 2.10	8.50	0.16
Ponderal index	3.19 ± 0.15	2.86 ± 0.24	10.48	0.28
Lower leg length, cm	37.25 ± 1.16	32.38 ± 1.15	13.09	0.02
Brain, g	47.71 ± 1.21	46.05 ± 3.72	3.48	0.69
Brain: fetal weight	0.0121 ± 0.000	0.0172 ± 0.002	42.63	0.03
Liver, g	100.33 ± 9.13	65.50 ± 15.80	34.71	0.10
Brain: liver	0.45 ± 0.03	0.79 ± 0.21	73.65	0.17
Liver: fetal weight	0.0267 ± 0.001	0.0247 ± 0.004	7.64	0.62
Left liver lobe, g	27.19 ± 4.53	17.74 ± 4.07	34.76	0.17
Right liver lobe, g	75.46 ± 3.24	47.88 ± 11.71	36.54	0.06
Heart, g	22.48 ± 1.79	17.28 ± 2.14	23.15	0.11
Heart: fetal weight	0.0056 ± 0.000	0.0063 ± 0.001	12.29	0.23
Left ventricle, g	9.02 ± 0.81	6.68 ± 0.48	25.91	0.05
Right ventricle, g	4.99 ± 0.32	3.81 ± 0.70	23.56	0.18
Lungs, g	123.18 ± 8.76	101.61 ± 15.44	17.51	0.27
Lungs: fetal weight	0.031 ± 0.001	0.0364 ± 0.001	17.31	0.01
Pancreas, g	3.25 ± 0.33	2.40 ± 0.42	26.21	0.16
Kidneys, g	20.05 ± 1.21	15.61 ± 2.33	22.17	0.14
Perirenal adipose tissue (PRAT), g	13.36 ± 1.96	10.58 ± 1.23	20.80	0.27
Spleen, g	6.48 ± 0.58	5.24 ± 1.24	19.24	0.40
Adrenal glands, g	0.32 ± 0.02	0.34 ± 0.06	4.38	0.86
Biceps femoris (BF), g	28.69 ± 1.22	17.97 ± 2.19	37.35	0.01
Soleus, g	0.35 ± 0.06	0.14 ± 0.04	60.28	0.02
Flexor digitorum superficialis (FDS), g	3.08 ± 0.27	1.93 ± 0.31	37.45	0.03
Tibialis anterior (TA), g	3.8 ± 0.35	2.37 ± 0.32	37.59	0.02
Extensor digitorum longus (EDL), g	1.01 ± 0.10	0.59 ± 0.10	42.22	0.03
Uteroplacental weight, g	1829.40 ± 136.67	1333.65 ± 207.93	27.10	0.09
Membrane weight, g	483.55 ± 32.18	470.28 ± 112.73	2.75	0.91
Total placentome, #	67.25 ± 4.09	71.75 ± 10.09	6.69	0.69

Data are shown as means ± SEM for all pregnancies in each treatment group. CSH, chorionic somatomammotropin; RNAi, RNA interference.