Table 2.
Normal Glucose Metabolism | PreDM | |||||
---|---|---|---|---|---|---|
W/Out IR n = 66 |
With IR n = 34 34% |
p * | W/Out IR n = 51 |
With IR n = 57 53% |
p * | |
Age (years), mean ± SD | 58 ± 7 | 54 ± 7 | 0.008 | 57 ± 7 | 58 ± 8 | 0.222 |
Women, (%) | 65.2 | 76.5 | 0.246 | 64.7 | 68.4 | 0.683 |
Current smokers, (%) | 12.1 | 11.8 | 0.959 | 13.7 | 7.0 | 0.250 |
Treatment with statin, (%) | 12.1 | 5.9 | 0.325 | 13.7 | 15.8 | 0.763 |
Treatment with antihypertensives (%) | 37.9 | 52.9 | 0.150 | 41.2 | 49.1 | 0.408 |
Antecedent of CVD (%) | 13.6 | 8.8 | 0.483 | 2.0 | 5.3 | 0.364 |
BMI (kg/m2), mean ± SD | 28.1 ± 4.4 | 30.5 ± 5.4 | 0.027 | 30.1 ± 5.4 | 32.1 ± 5.4 | 0.062 |
Systolic BP (mmHg), mean ± SD | 134 ± 19 | 135 ± 15 | 0.754 | 135 ± 14 | 139 ± 15 | 0.203 |
Diastolic BP (mmHg), mean ± SD | 82 ± 13 | 82 ± 10 | 0.964 | 82 ± 10 | 84 ± 11 | 0.503 |
FPG (mg/dL), mean ± SD | 89 ± 9 | 92 ± 10 | 0.140 | 107 ± 9 | 108 ± 9 | 0.640 |
LDL-Cholesterol (mgl/L), mean ± SD | 122 ± 33 | 122 ± 33 | 0.990 | 118 ± 40 | 128 ± 41 | 0.182 |
Triglycerides (mgl/L), mean ± SD | 100 ± 27 | 185 ± 70 | <0.001 | 102 ± 33 | 204 ± 85 | <0.001 |
HDL-Cholesterol (mgl/L), mean ± SD | 55 ± 9 | 42 ± 9 | 0.001 | 57 ± 14 | 43 ± 9 | <0.001 |
Pulse wave velocity (m/sec), mean ± SD | 7.7 ± 2.0 | 7.9 ± 2.0 | 0.615 | 7.4 ± 1.8 | 8.3 ± 2.3 | 0.024 |
* Continuous variables were compared using t-test for independent samples and proportions using χ2 test. PreD: prediabetes; IR: insulin resistance; HDL: high-density lipoprotein; LDL: low-density lipoprotein; BP: Blood pressure; FPG: Fasting glucose; BMI: body mass index; CVD: cardiovascular disease; TG/HDL: triglyceride/high-density lipoprotein cholesterol ratio.