| ANOVA | Analysis of variance |
| AQbD | Analytical Quality by Design |
| ASD | Asymmetric screening design |
| BBD | Box-Behnken design |
| BGE | background electrolyte |
| CCC | Central composite circumscribed design |
| CCD | Central composite design |
| CD | cyclodextrin |
| CE | capillary electrophoresis |
| CEC | capillary electrochromatography |
| CE-MS | capillary electrophoresis—mass spectrometry |
| CE-ESI-MS | capillary electrophoresis coupled with electrospray ionization mass spectrometry |
| CMA | Critical Method Attribute |
| CMP | Critical Method Parameter |
| CM-β-CD | carboxymethyl-β-cyclodextrin |
| CPP | critical process parameter |
| CQA | critical quality attributes |
| CS | chiral selector |
| CSP | chiral stationary phase |
| CZE | capillary zone electrophoresis |
| D-oD | D-optimal design |
| D-Phe | D-Phenylalanine |
| DoE | Design of Experiments |
| DD | Doehlert design |
| DM-β-CD | dimethyl-β-cyclodextrin |
| DS | Design Space |
| EMA | European Medicines Agency |
| EOF | electroosmotic flow |
| FDA | Food and Drug Administration |
| FCCD | Face centered central composite design |
| FFD | Full factorial design |
| FLEC | l-(9-fluorenyl)ethyl chloroformate |
| FMOC | 9-fluorenylmethyl chloroformate |
| FrFD | Fractional factorial design |
| HDAS-β-CD | heptakis(2,3-di-O-acetyl-6-O-sulfo)-β-cyclodextrin |
| HDM-β-CD | heptakis-2,6-di-O-methyl-β-cyclodextrin |
| HDMS-β-CD | heptakis-(2,3-di-O-methyl-6-O-sulfo)-β-cyclodextrin |
| HES-β-CD | heptakis-6-sulfato-β-CD |
| HMAS-β-CD | heptakis(2-O-methyl-3-O-acetyl-6-O-sulfo)-β-cyclodextrin |
| HPLC | high performance liquid chromatography |
| HP-β-CD | hydroxypropyl-β-cyclodextrin |
| HP-γ-CD | hydroxypropyl-γ-cyclodextrin |
| HS-β-CD | highly sulphated-β-cyclodextrin |
| HTM-β-CD | heptakis (2,3,6-tri-O-methyl)-β-cyclodextrin |
| HSA | human serum albumin |
| ICH | International Council for Harmonisation |
| LIF | laser induced fluorescence |
| LOD | limit of detection |
| LOQ | limit of quantification |
| M-α-CD | methyl-α-cyclodextrin |
| M-β-CD | methyl-β-cyclodextrin |
| M-γ-CD | randomly methylated γ-cyclodextrin |
| MDA | 3,4-methylenedioxyamphetamine |
| MDEA | 3,4-methylenedioxyethylamphetamine |
| MDMA | 3,4-methylenedioxymethamphetamine |
| MEKC | micellar electrokinetic chromatography |
| MODR | Method operable design region |
| NACE | nonaqueous capillary electrophoresis |
| OAD | Orthogonal array design |
| ODMS-γ-CD | octakis(2,3-di-O-methyl-6-O-sulfo)-γ-cyclodextrin |
| OFAT | one factor at a time |
| PBD | Plackett-Burman design |
| PEG | polyethylene glycol |
| PO | polar organic |
| QbD | Quality by Design |
| RP | reverse phase |
| RSM | Response Surface Methodology |
| S-β-CD | sulfated-β-CD |
| S-γ-CD | sulfated-γ-CD |
| SBE-β-CD | sulfobutylether-β-cyclodextrin |
| SDS | sodium dodecyl sulfate |
| S/N | signal-to-noise |
| SSD | Symmetric screening design |
| SNRI | serotonin and norepinephrine reuptake inhibitor |
| SSRI | selective serotonin reuptake inhibitor |