Table 4.
Dissolvable/swellable microneedle devices. Adapted with permission from [59].
| Drugs | Polymers | Types | Reference |
|---|---|---|---|
| Dihydroergotamine mesylate | Polyvinylpyrrolidone | Dissolving | [60] |
| Thymopentin | Polyvinylpyrrolidone | Dissolving | [61] |
| Exendin-4 | Carboxymethylcellulose | Dissolving | [62] |
| Fluorescent Model | HA/PVA | Dissolving | [63] |
| Sumatriptan succinate | Polyvinylpyrrolidone | Dissolving | [64] |
| Adenosine | Hyaluronic acid | Dissolving | [65] |
| Vitamin K | Gantrez® S-97 * | Dissolving | [66] |
| Lysozyme | Polyvinylpyrrolidone | Dissolving | [67] |
| Valproic acid | Carboxymethylcellulose | Dissolving | [68] |
| Besifloxacin | Polyvinylpyrrolidone | Dissolving | [69] |
| Caffeine/Theophylline | Hydrolyzed PEVE-MA and PEG | Swellable extraction of fluid | [70] |
| Glucose/Cholesterol | Methacrylated HA | Swellable extraction of fluid | [71] |
| FITC-dextran | Silk fibroin | Swellable | [72] |
| Curcumin | Gantrez® S-97 PEVE-MA and Tween 85 | Swellable | [73] |
PEVE-MA: Poly(methyl vinyl ether-alt-maleic anhydride); PEG: poly(ethyleneglycol); HA: hyaluronic acid, * Gantr Gantrez® S-97 is a copolymer of maleic acid and methyl vinyl ether.