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. 2021 May 1;29(7):635–647. doi: 10.1016/j.jsps.2021.04.025

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© 2021 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Main effect plots of (A) the polymer type on the three responses, when other factors maintained at their middle values. Note the D-optimal design has no centre points and hence were not displayed. (B) The polymer concentration on disintegration time and film thickness uniformity when other factors maintained at their middle values. Note the D-optimal design has no centre points and hence were not displayed. (C) Interaction effect plot of polymer type with increasing polymer concentration on disintegration time and content uniformity while the other factors were maintained at their middle values. (D) Interaction effect plot of polymer concentration with plasticizer type on disintegration time and content uniformity while the other factors were maintained at their middle values.