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DOX in OLND promotes synergistic antitumor effects. Cell viability was evaluated by MTT assay. Data are expressed as percentage vs. control. TUBO cells were left untreated or incubated for 48 h with DOX (0.005 μM), OLNDs (2.5% v/v) or DOX-loaded OLNDs (0.005 μM/2.5% v/v). Results are shown as means ± SD from three independent experiments. Significance of the differences: * p < 0.05; ** p < 0.005; *** p < 0.001.
