Figure 1.
Expression levels of mature miR-146b-5p (A) and miR-146b-3p (B) in human thyroid cancer cell lines derived from PTC (BCPAP) or ATC (KTC2, 8305C, C643, Hth74 and Hth83), and as non-malignant control Nthy ori 3-1. Gene expression was calculated with Qgene using 2−deltact. Grey bars indicate the presence of mutation BRAFV600E and black bars indicate the presence of RAS mutations, or NF1 (dashed bar). (C) Ratio between miR-146b-5p/miR-146b-3p expression levels calculated from data shown in panel (A) and panel (B).