Table 3.

Evidence of dysregulated clock gene expression in GBM.

Gene	Evidence of Gene Deregulation Associated with Gliomagenesis—Evidence of Potentiality for Therapeutic Targeting
Clock	[209,211,213,219,223,224,225,226,227]
Bmal1	[21,22,161,209,219,220,221,222]
Per1	[21,161,213,225,227,228,229,230,231]
Per2	[213,227,228,230,231,232,233]
Per3	[213,225,227,231]
Cry1	[209,222,225,227,231,234]
Cry2	[213,222,225,231,234,235]
Npas2	[225,227]
Rev-erb	[209,212,213,219,241,242]
RORα	[213]
RORβ	[213]
Timeless	[227,243]

Summary of references available in the literature regarding the implication of circadian clock genes in the biology of GBM.