Table 3.
Adjusted ORs of number of maternal education and psychological distress for CHDs (Multiple imputation, 93,643)
| Crude | Model 1 | Model 2 | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Proportiona | OR | 95%CI | P | P for trend | OR | 95%CI | P | P for trend | OR | 95%CI | P | P for trend | |||||||
| Number of positiveb | |||||||||||||||||||
| 0 | 92.0% | 1.00 | 0.011 | 1.00 | 0.043 | 1.00 | 0.050 | ||||||||||||
| 1 | 7.6% | 1.25 | 1.00 | - | 1.55 | 0.052 | 1.20 | 0.95 | - | 1.52 | 0.123 | 1.20 | 0.95 | - | 1.51 | 0.135 | |||
| 2 | 0.4% | 2.02 | 0.97 | - | 4.24 | 0.062 | 1.87 | 0.88 | - | 3.99 | 0.103 | 1.83 | 0.86 | - | 3.91 | 0.117 | |||
| P for interaction term | 0.563 | 0.573 | 0.589 | ||||||||||||||||
aMean proportion of each category in the imputed 25 datasets
bNumber of mother junior high school or psychological distress positive
Model 1: All listed variables, maternal age, mother BMI, household income father education, marital status, mother drinking habit, mother smoking, paternal smoking, parity, infant sex, plurality, fertility treatment, hypertensive disorder during pregnancy, thyroid diseases during pregnancy, diabetes mellitus/gestational diabetes during pregnancy, folic acid supplementation during early pregnancy, and mother congenital heart diseases are introduced
Model 2: All variables in Model 1 and anti-depressant use are introduced
P for trend: The number of positives (0–2) was introduced into the model
P for interaction term: Mothers’ lowest education (EDC1), psychological distress, and their interaction term were introduced into the model