Table 2.

Associations between maternal glycemia and change in ¹³C-DHA lipids with in-vitro glucose treatment (glucose response) in placental explants (n = 17)

13C-DHA lipid	Fasting glycemiaa		Post load glycemia (2 h)a
	Estimate (lower CI, upper CI) Relative amountb/ (mmol/L)	p value (BH)	Estimate (lower CI, upper CI) Relative amountb/ (mmol/L)	p value (BH)
DG 38:6	0.106 (− 0.45, 0.663)	0.911	− 0.091 (− 0.241, 0.059)	0.216
DG 40:7	0.065 (− 0.542, 0.673)	0.822	− 0.108 (− 0.27 ,0.053)	0.172
DG 40:8	0.116 (− 0.506, 0.739)	0.919	− 0.093 (− 0.262, 0.076)	0.261
LPC 22:6	− 0.688 (− 1.732, 0.355)	0.18	− 0.228 (− 0.515, 0.059)	0.111
LPE 22:6	− 0.82 (− 2.092, 0.451)	0.189	− 0.26 (− 0.613, 0.093)	0.137
PC 38:6	− 0.474 (− 0.993, 0.046)	0.071	− 0.111 (− 0.264, 0.041)	0.139
PE-P 38:6	− 0.034 (− 0.45, 0.382)	0.912	− 0.079 (− 0.189, 0.03)	0.186
PE-P 40:6	− 0.196 (− 0.612, 0.219)	0.329	− 0.055 (− 0.172, 0.062)	0.338
TG 54:6	− 0.164 (− 0.741, 0.414)	0.555	− 0.075 (− 0.235, 0.085)	0.334
TG 54:7	− 0.123 (− 0.658, 0.413)	0.632	− 0.059 (− 0.208, 0.09)	0.412
TG 56:6	− 0.243 (− 0.823, 0.337)	0.387	− 0.06 (− 0.225, 0.105)	0.451
TG 56:7	− 0.128 (− 0.729, 0.474)	0.658	− 0.037 (− 0.207, 0.133)	0.65
TG 56:8	− 0.042 (− 0.647, 0.562)	0.883	− 0.053 (− 0.221, 0.115)	0.512
TG 56:9	− 0.256 (− 1.065, 0.553)	0.511	− 0.117 (− 0.34, 0.106)	0.28
TG 58:8	0.112 (− 0.398, 0.622)	0.89	− 0.01 (− 0.155, 0.135)	0.881
TG 58:9	− 0.086 (− 0.628, 0.457)	0.741	− 0.076 (− 0.224, 0.072)	0.289
TG 58:10	0.009 (− 0.649, 0.668)	0.976	− 0.052 (− 0.236, 0.132)	0.553

CI confidence interval, BH Benjamini–Hochberg corrected

^aIn mid-gestation 75 g three time-point OGTT

^bChange in ¹³C-DHA lipid with glucose treatment or glucose response (log2-fold-change) represents the relative amount of ¹³C-DHA lipid in placental explants treated with glucose (10 mmol/L) compared to control explants from the same placenta. Positive values indicate an increase in ¹³C-DHA lipids compared to the control, whilst negative values indicate a decrease