TABLE 1.
Characteristics of the 100 study participants enrolled in this randomized controlled trial1
| Placebo | Citicoline | ||
|---|---|---|---|
| (n = 51) | (n = 49) | P | |
| Age,2 y | 65.5 ± 1.13 | 63.2 ± 1.12 | 0.53 |
| Gender,3 n (%) | |||
| Male | 16 (31.4) | 19 (38.8) | |
| Female | 35 (68.6) | 30 (61.2) | 0.16 |
| Race,3n (%) | 0.17 | ||
| White | 47 (92.2) | 41 (83.7) | |
| Black/African American | 3 (5.88) | 7 (14.3) | |
| American Indian or Alaskan Native | 0 (0.00) | 1 (2.04) | |
| Asian | 0 (0.00) | 0 (0.00) | |
| Native Hawaiian or other Pacific Islander | 1 (1.92) | 0 (0.00) | |
| Ethnicity,3n (%) | 1.00 | ||
| Not Hispanic/Latino | 49 (96.1) | 48 (98.0) | |
| Hispanic/Latino | 2 (3.92) | 1 (2.04) | |
| BMI,2 kg/m2 | 29.6 ± 0.96 | 30.7 ± 0.91 | 0.35 |
| Systolic BP,2 mm Hg | 127 ± 2.06 | 130 ± 1.83 | 0.25 |
| Diastolic BP,2 mm Hg | 74.4 ± 1.64 | 76.1 ± 1.38 | 0.44 |
| MMSE2 | 27.6 ± 0.22 | 27.8 ± 0.21 | 0.50 |
| KBIT-22 | 101 ± 1.45 | 98.9 ± 1.26 | 0.30 |
| Geriatric Depression Scale2 | 0.784 ± 0.144 | 0.796 ± 0.124 | 0.95 |
| Spatial Span score (at screening)2 | 3.71 ± 0.08 | 3.80 ± 0.06 | 0.35 |
| Hours of sleep (at Week 0),2 h | 7.32 ± 0.12 | 7.20 ± 0.11 | 0.47 |
1
Values are means ± SEMs or frequency (%). Differences between placebo and citicoline groups for all characteristics were analyzed using independent t-test for continuous variables and Fisher's exact test for categorical variables. BP, blood pressure; kg, kilogram; KBIT-2, Kaufman Brief Intelligence Test, Second Edition; m, meter; mm Hg, millimeter mercury; MMSE, Mini-Mental State Examination.
2
Independent t-test.
3
Fisher's exact test.