Table 3.

Drug-likeness properties (Lipinski’s rule of five) of investigated natural products and reference compounds as predicted by QikProp

s/n	Name	mol_MWa	donorHBc	donorHBd	QPlogPo/wb	RuleOfFivee
1	STOCK1N-98687	452.463	4.25	9	0.946	0
2	STOCK1N-89003	487.465	3	9.75	1.542	0
3	STOCK1N-84615	420.381	5	8	0.35	0
4	STOCK1N-84519	365.342	2	8.25	0.672	0
5	STOCK1N-92347	492.576	1	5.75	6.224	1
6	STOCK1N-94719	489.481	4	9.7	2.135	0
7	Lopinavir	628.81	4	9.45	5.608	2
8	STOCK1N-98135	416.473	3.25	8.25	1.469	0
9	STOCK1N-80093	456.451	5	13.5	0.465	0
10	STOCK1N-93501	493.564	1	6	5.894	1
11	Ivermectin	730.977	1	11.75	7.484	2

^aMolecular weight of the molecule (Range 130.0 to 725.0)

^bPredicted octanol/water partition coefficient. (Range − 2.0 to 6.5)

^cNumberof hydrogen bond donors (Range 0.0 to 6.0)

^dNumber of hydrogen bond acceptors (Range 2.0 to20.0)

^eNumber of violations of Lipinski’s rule of five (Range maximum is 4)