Table 3.
Signaling Pathways Most Strongly Associated with DTYMK Expression Level Based on Their Normalized Enrichment Score (NES) and p-value
| (A) GO Annotation | |||||||
|---|---|---|---|---|---|---|---|
| GO Name | NES | NOM p-value | FDR q-value | ||||
| Negative | GO_Protein_Activation_Cascade | −2.17949 | 0 | 0.024736 | |||
| GO_Monooxygenase_Activity | −2.11688 | 0 | 0.039394 | ||||
| GO_Androgen_Metabolic_Process | −2.09886 | 0 | 0.036316 | ||||
| GO_Organic_Acid_Catabolic_Process | −2.07874 | 0.001901 | 0.038857 | ||||
| GO_Monocarboxylic_Acid_Catabolic_Process | −2.06001 | 0 | 0.041592 | ||||
| Positive | GO_DNA_Biosynthetic_Process | 2.377608 | 0 | 0.002169 | |||
| GO_Negative_Regulation_of_Cell_Cycle_Phase_Transition | 2.336135 | 0 | 0.001865 | ||||
| GO_Negative_Regulation_of_Cell_Cycle_Process | 2.294165 | 0 | 0.004995 | ||||
| GO_Condensed_Chromosome_Centromeric_Region | 2.29015 | 0 | 0.003746 | ||||
| GO_Signal_Transduction_Involved_in_Cell_Cycle_Checkpoint | 2.266043 | 0 | 0.004237 | ||||
| (B) KEGG Annotation | |||||||
| KEGG Name | NES | NOM p-value | FDR q-value | ||||
| Negative | KEGG_Fatty_Acid_Metabolism | −2.32252 | 0 | 0 | |||
| KEGG_Complement_and_Coagulation_Cascades | −2.29765 | 0 | 0 | ||||
| KEGG_Drug_Metabolism_Cytochrome_P450 | −2.18277 | 0 | 0.002823 | ||||
| KEGG_Valine_Leucine_and_Isoleucine_Degradation | −2.16062 | 0.002083 | 0.002763 | ||||
| KEGG_Tryptophan_Metabolism | −2.11349 | 0 | 0.004277 | ||||
| Positive | KEGG_Base_Excision_Repair | 2.260003 | 0 | 0.009595 | |||
| KEGG_Pyrimidine_Metabolism | 2.239599 | 0 | 0.004797 | ||||
| KEGG_Homologous_Recombination | 2.221476 | 0 | 0.004391 | ||||
| KEGG_DNA_Replication | 2.135919 | 0 | 0.006331 | ||||
| KEGG_Cell_Cycle | 2.127497 | 0 | 0.005757 | ||||