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. 2021 Aug 3;17:2511–2525. doi: 10.2147/NDT.S320680

Table 2.

MTHFR Polymorphisms in Patients of Different Onset Ages

Sites C677T A1298C G1793A
CC CT TT C T AA AC CC A C GG GA AA G A
Early
Total 25 52 37 102 126 79 32 3 190 38 98 16 0 212 16
HWE 0.411 0.910 0.422
Adult
Total 15 29 19 59 67 52 10 1 114 12 58 5 0 121 5
HWE 0.481 0.379 0.678
χ2Total 0.133 0.143 3.701 3.414 1.443 1.352
df 2 1 2 1 2 1
 p 0.9358 0.7055 0.1572 0.0647 0.2296 0.2449

Note: Comparison in genotype and allele frequencies of three polymorphisms in patients of different onset ages.

Abbreviation: HWE, Hardy Weinberg Equilibrium.