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. 2021 Aug 8;40(12):1579–1588. doi: 10.1016/j.healun.2021.07.026

Table 3.

Median Semiquantitative SARS-CoV-2 Anti-Spike Antibody Immunoassay Results of Heart and Lung Transplant Recipients by Antibody Response

D1
D2
Roche Elecsys EUROIMMUN Roche Elecsys EUROIMMUN
U/mL (IQR) (IQR) U/mL (IQR) (IQR)
n = 183 n = 54 n = 183 N = 54
Priming dose responders 2.9 (1.1, 11.5) 2.4 (2.3, 2.5) 250 (174, 250) 9.1 (7.2, 9.4)
Booster responders 0 (0, 0) 0.2 (0.03, 0.5) 23.8 (3.9, 244.2) 5.5 (2.1, 8.0)
Non-responders 0 (0, 0) 0.1 (0.03, 0.2) 0 (0, 0) 0.2 (0.1, 0.5)

Anti-RBD immunoassay (Roche Elecsys) results are reported as a concentration of immunoglobulin G (IgG) against the target protein with a measurement range of 0.4 to 250 U/mL; results ≥250 U/mL are reported as 250 U/mL. Anti-S1 immunoassay (EUROIMMUN) results are reported as a sample-to-control ratio of optical density. Antibody-positive cut-offs (determined by the manufacturer) were ≥0.80 U/mL for the former and ≥1.1 arbitrary units for the latter. Priming dose responders developed positive results after both D1 and D2. Booster responders developed positive results only after D2. Non-responders maintained negative results after D1 and D2. D1/D2; Dose1/2. RBD; Receptor binding domain.