Table 1.
Stability of PACAP1-27 in different media and conditions over a period of 2 weeks. The numbers in the cells indicate the percentage of the starting material that was not decomposed on the given day
| PACAP1-27 | 0.9% Saline solution | Benzalkonium chloride solution for ophthalmic use (SOCB) | Thimerosal solution for ophthalmic use | Water for injection | ||||
|---|---|---|---|---|---|---|---|---|
| RT | +4 °C | RT | +4 °C | RT | +4 °C | RT | +4 °C | |
| Day 3 | 76 | 96 | 72 | 91 | 49 | 93 | 80 | 98 |
| Day 6 | 73 | 91 | 59 | 78 | 44 | 84 | 52 | 95 |
| Day 8 | 54 | 89 | 31 | 77 | 30 | 82 | 38 | 92 |
| Day 11 | 43 | 83 | 24 | 72 | 27 | 70 | 37 | 91 |
| Day 14 | 39 | 79 | 7 | 65 | 22 | 62 | 25 | 90 |
RT room temperature