Table 2.
Stability of PACAP1-38 in different media and conditions over a period of 2 weeks. The numbers in the cells indicate the percentage of the starting material that was not decomposed on the given day
PACAP1-38 | 0.9% Saline solution | Benzalkonium chloride solution for ophthalmic use (SOCB) | Thimerosal solution for ophthalmic use | Water for injection | ||||
---|---|---|---|---|---|---|---|---|
RT | +4 °C | RT | +4 °C | RT | +4 °C | RT | +4 °C | |
Day 3 | 93 | 99 | 98 | 99 | 96 | 99 | 96 | 100 |
Day 6 | 77 | 99 | 93 | 93 | 84 | 94 | 92 | 99 |
Day 8 | 68 | 96 | 84 | 91 | 77 | 89 | 92 | 95 |
Day 11 | 67 | 93 | 81 | 83 | 73 | 85 | 89 | 94 |
Day 14 | 45 | 92 | 68 | 77 | 64 | 79 | 87 | 91 |
RT room temperature