Fig. 4.

Microscopic images of haematoxylin and eosin staining of the explanted lungs.

A: chronic scarring with architectural destruction in the form of a microcystic appearance (black arrows) of the pulmonary parenchyma due to dilated alveolar spaces.

B: significant vascular changes with a significant amount of new vessel growth and fibrous and oedematous thickening of the media (black arrows) with very few thrombi. Interstitial fibrosis (red arrow).

C: traction bronchiectasis (black arrow) with peribronchiolar metaplasia (red arrow) and vascular changes with fibrosis thickening of small vessel walls (blue arrow).

D: interstitial fibrosis (red arrow) with mild to moderate interstitial inflammation composed of lymphocytes and plasma cells. Type II hyperplasia of the pneumocytes (black arrow).